Our research concerns the interdisciplinary field of bioinformatics. We are interested in algorithm development to solve problems of molecular biology. This ranges from protein structure analysis to computational systems biology.
Computational Systems Biology
• Qualitative and quantitative modeling of biochemical processes in metabolic networks, in signal transduction networks, and in gene regulatory networks
• Adaption and extension of Petri net-based techniques for exploring biochemical systems
• Modeling of cell-cell communication
Structural Bioinformatics
• Protein structure topology, protein structure comparison
• Protein-Ligand interactions, protein-protein interactions
• Structural aspects of alternative splice sites
Analysis and assembly of protein structure complexes
Methods
• Graph theory and graph algorithms in computational chemistry, biology, and computational systems biology
• Petri nets, Boolean networks, Agent-based models